Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | BCR | P11274 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10931037 | 0.83 | ALOX5 (0.53) | ESR2ALOX5NCOA1NCOA3L3MBTL1 | |
| SCHEMBL8375486 | 0.83 | MEN1 (0.47) | ESR2MAPT | |
| SCHEMBL9859720 | 0.81 | NCOA1 (0.52) | SCN9ANCOA1NCOA3L3MBTL1BRD4 | |
| SCHEMBL9842220 | 0.81 | SCN9A (0.46) | SCN9ANCOA1NCOA3L3MBTL1BRD4 | |
| SCHEMBL9298320 | 0.81 | NCOA1 (0.58) | SCN9ANCOA1NCOA3L3MBTL1BRD4 | |
| SCHEMBL5032967 | 0.80 | CYP3A4 (0.44) | ESR2 | |
| SCHEMBL5450397 | 0.79 | ALOX5 (0.65) | ESR2ALOX5KDM4EMAPTPELI1 | |
| SCHEMBL5082815 | 0.78 | LTA4H (0.52) | ESR2KDM4E | |
| SCHEMBL23928778 | 0.77 | ABL1 (0.54) | ESR2ALOX5NCOA1NCOA3KDM4E | |
| SCHEMBL112422 | 0.76 | NCOA1 (0.63) | SCN9ANCOA1NCOA3L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446722-A1 | Novel hydroxylated phenoxy compounds and process for their preparation | Bromine Compounds Ltd. (IL) | 1991-09-18 | — | — | EP | claimed |
| EP-0446722-A1 | Novel hydroxylated phenoxy compounds and process for their preparation | Bromine Compounds Ltd. (IL) | 1991-09-18 | — | — | EP | disclosed |