Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853789 | 0.85 | MERTK (0.48) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL7055435 | 0.85 | ALDH1A1 (0.45) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL4376514 | 0.82 | LMNA (0.42) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL4375480 | 0.82 | PDE7A (0.49) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL4377981 | 0.81 | MEN1 (0.48) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL31460910 | 0.79 | MAPT (0.62) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL21067091 | 0.77 | NPC1 (0.46) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL9853579 | 0.76 | PIN1 (0.47) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL4383031 | 0.75 | EPAS1 (0.44) | MAPTALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL2885107 | 0.75 | ALDH1A1 (0.55) | MAPTALDH1A1LMNAKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4959377-A | Phenoxypyridinamine compounds which are use as a dermatological composition | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-09-25 | — | — | US | claimed |
| EP-0405487-A1 | Phenoxypyridinamines and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-01-02 | — | — | EP | disclosed |
| US-4959377-A | Phenoxypyridinamine compounds which are use as a dermatological composition | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-09-25 | — | — | US | disclosed |