Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7055435 | 0.88 | ALDH1A1 (0.45) | MERTKSMN1; SMN2KMT2AALDH1A1TDP1 | |
| SCHEMBL4376514 | 0.85 | LMNA (0.42) | MERTKSMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL4375480 | 0.85 | PDE7A (0.49) | MERTKSMN1; SMN2KMT2AALDH1A1TDP1 | |
| SCHEMBL4377981 | 0.85 | MEN1 (0.48) | SMN1; SMN2KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL9853822 | 0.85 | MAPT (0.46) | SMN1; SMN2KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL2885107 | 0.84 | ALDH1A1 (0.55) | SMN1; SMN2KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL9853579 | 0.79 | PIN1 (0.47) | SMN1; SMN2KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL4383031 | 0.78 | EPAS1 (0.44) | MERTKKMT2AALDH1A1TDP1MAPT | |
| SCHEMBL9853586 | 0.78 | L3MBTL1 (0.51) | SMN1; SMN2KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL9853587 | 0.77 | ALDH1A1 (0.37) | SMN1; SMN2KMT2AALDH1A1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4959377-A | Phenoxypyridinamine compounds which are use as a dermatological composition | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-09-25 | — | — | US | claimed |
| JP-3038568-A | — | — | None | — | — | JP | disclosed |
| JP-H0338568-A | PHENOXYPYRIDINAMINES AND ITS PREPARATION | HOECHST ROUSSEL PHARMACEUT INC | 1991-02-19 | — | — | JP | disclosed |
| EP-0405487-A1 | Phenoxypyridinamines and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-01-02 | — | — | EP | disclosed |
| US-4959377-A | Phenoxypyridinamine compounds which are use as a dermatological composition | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1990-09-25 | — | — | US | disclosed |