Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 3/20 | 0.52 |
| ▸ | TUBB | P07437 | 3/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.52 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.52 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.52 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.52 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.52 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.52 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.52 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.52 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.52 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.52 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.52 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10397869 | 0.86 | LMNA (0.67) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9089602 | 0.77 | CALM1 (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL25253512 | 0.76 | PDK1 (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3892580 | 0.75 | KAT6A (0.50) | CYP4F2CYP4A11 | |
| SCHEMBL7138097 | 0.75 | HDAC1 (0.44) | CYP19A1CYP4F2CYP4A11 | |
| SCHEMBL21530612 | 0.74 | TUBB4A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28275397 | 0.74 | TUBB4A (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL219096 | 0.74 | TUBB4A (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4464142 | 0.74 | HTR2A (0.75) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2133327 | 0.73 | MRGPRX4 (0.49) | LMNAKMT2AMEN1CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425134-A1 | Condensed pyrrolo derivatives, process for their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |