Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 8/20 | 0.67 |
| ▸ | CCKBR | P32239 | 4/20 | 0.59 |
| ▸ | ECE1 | P42892 | 2/20 | 0.57 |
| ▸ | CTSD | P07339 | 1/20 | 0.56 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.55 |
| ▸ | IL1RN | P18510 | 1/20 | 0.54 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30721645 | 0.89 | CCKBR (0.64) | KISS1RCCKBRECE1 | |
| SCHEMBL9854726 | 0.88 | CCKBR (0.66) | KISS1RCCKBR | |
| SCHEMBL11569573 | 0.88 | KISS1R (0.63) | KISS1RCCKBRECE1ERAP2IL1RN | |
| SCHEMBL10380385 | 0.87 | GHSR (0.60) | KISS1RCCKBR | |
| SCHEMBL9854705 | 0.84 | MMP1 (0.50) | KISS1R | |
| SCHEMBL2494516 | 0.82 | KISS1R (0.73) | KISS1R | |
| Desglugastrin SCHEMBL30390255 | 0.82 | CCKBR (0.69) | CCKBR | |
| Desglugastrin SCHEMBL1371702 | 0.82 | CCKBR (0.69) | CCKBR | |
| Hydrochloric Acid SCHEMBL10419482 | 0.82 | KISS1R (0.68) | KISS1RECE1 | |
| SCHEMBL30307612 | 0.82 | OPRM1 (0.67) | KISS1RCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405506-A1 | Tetrapeptide type-B CCK receptor ligands | ABBOTT LABORATORIES (US) | 1991-01-02 | — | — | EP | disclosed |