Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 13/20 | 0.69 |
| ▸ | CCKAR | P32238 | 1/20 | 0.67 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.67 |
| ▸ | NPBWR1 | P48145 | 6/20 | 0.63 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Desglugastrin SCHEMBL30390255 | 1.00 | CCKBR (0.69) | CCKBRCCKAROPRD1NPBWR1IL23R | |
| Desglugastrin SCHEMBL1230299 | 0.96 | CCKBR (0.64) | CCKBRCCKAROPRD1NPBWR1IL23R | |
| SCHEMBL30721654 | 0.91 | CCKBR (0.72) | CCKBRCCKAROPRD1NPBWR1 | |
| SCHEMBL30307612 | 0.90 | OPRM1 (0.67) | CCKBRCCKAROPRD1 | |
| SCHEMBL11659149 | 0.87 | CCKBR (0.68) | CCKBROPRD1 | |
| SCHEMBL11666813 | 0.87 | CCKBR (0.68) | CCKBROPRD1 | |
| SCHEMBL29414561 | 0.87 | CCKBR (0.80) | CCKBRCCKAROPRD1NPBWR1 | |
| SCHEMBL29360483 | 0.87 | CCKBR (0.79) | CCKBRCCKARNPBWR1IL23R | |
| SCHEMBL11662175 | 0.86 | CCKBR (0.69) | CCKBR | |
| SCHEMBL31015845 | 0.85 | CCKBR (0.82) | CCKBRCCKAROPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782649-B1 | BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS | ASCENDIS PHARMA AS (DK) | 2025-05-14 | — | — | EP | disclosed |
| US-20230381323-A1 | RELEASABLE CONJUGATES | FISH & RICHARDSON PC | 2023-11-30 | — | — | US | disclosed |
| US-11786599-B2 | Releasable conjugates | QUIAPEG PHARMACEUTICALS AB (SE) | 2023-10-17 | — | — | US | disclosed |
| US-20230123784-A1 | Biodegradable Polyethylene Glycol Based Water-Insoluble Hydrogels | ASCENDIS PHARMA A/S (DK) | 2023-04-20 | — | — | US | disclosed |
| US-20230065814-A1 | CONJUGATES OF-ELECTRON-PAIR-DONATING HETEROAROMATIC NITROGEN-COMPRISING COMPOUNDS | ASCENDIS PHARMA A/S (DK) | 2023-03-02 | — | — | US | disclosed |
| US-11559482-B2 | Biodegradable polyethylene glycol based water-insoluble hydrogels | ASCENDIS PHARMA A/S (DE) | 2023-01-24 | — | — | US | disclosed |
| US-20220305129-A1 | CONJUGATES OF HETEROAROMATIC NITROGEN-COMPRISING COMPOUNDS | ASCENDIS PHARMA A/S (DK) | 2022-09-29 | — | — | US | disclosed |
| EP-4011396-A1 | RELEASABLE CONJUGATES | QuiaPEG Pharmaceuticals AB (SE) | 2022-06-15 | — | — | EP | disclosed |
| EP-3986477-A1 | CONJUGATES OF pi-ELECTRON-PAIR-DONATING HETEROAROMATIC NITROGEN-COMPRISING COMPOUNDS | Ascendis Pharma A/S (DK) | 2022-04-27 | — | — | EP | disclosed |
| EP-3986472-A1 | CONJUGATES OF HETEROAROMATIC NITROGEN-COMPRISING COMPOUNDS | Ascendis Pharma A/S (DK) | 2022-04-27 | — | — | EP | disclosed |
| WO-2008127640-A2 | SUBSTITUTED BENZIMIDAZOLES | AUSPEX PHARMACEUTICALS, INC. (US) | 2008-10-23 | — | — | WO | disclosed |
| US-20080255200-A1 | SUBSTITUTED BENZIMIDAZOLES | AUSPEX PHARMACEUTICALS, INC. (US) | 2008-10-16 | — | — | US | disclosed |
| EP-1934201-A1 | DEUTERATED INHIBITORS OF GASTRIC H+, K+-ATPASE WITH ENHANCED THERAPEUTIC PROPERTIES | Auspex Pharmaceuticals Inc. (US) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007041630-A1 | DEUTERATED INHIBITORS OF GASTRIC H+, K+-ATPASE WITH ENHANCED THERAPEUTIC PROPERTIES | AUSPEX PHARMACEUTICALS, INC. (US) | 2007-04-12 | — | — | WO | disclosed |
| US-20070082929-A1 | Inhibitors of the gastric H+, K+-atpase with enhanced therapeutic properties | AUSPEX PHARMACEUTICALS, INC. | 2007-04-12 | — | — | US | disclosed |
| EP-0203031-B1 | BIOLOGICALLY ACTIVE LYSINE CONTAINING OCTAPEPTIDES | The Administrators of The Tulane University Educational Fund (US) | 1992-07-29 | — | — | EP | disclosed |
| EP-0302466-B1 | CYCLOPEPTIDES AS ABSORPTION ENHANCERS FOR ADMINISTRATION ON THE MUCOUS MEMBRANES | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-21 | — | — | EP | disclosed |
| US-4725577-A | Biologically active lysine containing octapeptides | ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 1988-02-16 | — | — | US | disclosed |
| US-4650787-A | SOMATOSTATIN ANALOG | ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND OF NEW ORLEANS, LOUISIANA, THE, | 1987-03-17 | — | — | US | disclosed |
| EP-0203031-A2 | Biologically active lysine containing octapeptides | The Administrators of The Tulane University Educational Fund (US) | 1986-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070082929-A1 | Inhibitors of the gastric H+, K+-atpase with enhanced therapeutic properties | ATP4A, ATP6V1G1, ATP6V1E1 | CCKBR 313/4885CCKAR 765/4885OPRD1 2752/4885 |
| US-20230123784-A1 | Biodegradable Polyethylene Glycol Based Water-Insoluble Hydrogels | PLG, PHYKPL, PLOD3 | CCKBR 631/4885CCKAR 1585/4885OPRD1 3338/4885 |
| US-20220305129-A1 | CONJUGATES OF HETEROAROMATIC NITROGEN-COMPRISING COMPOUNDS | NQO1, ABCB1, NCL | CCKBR 1422/4885CCKAR 1861/4885OPRD1 284/4885 |
| US-20230381323-A1 | RELEASABLE CONJUGATES | GUSB, ABCB11, UGT2B7 | CCKBR 1391/4885CCKAR 2453/4885OPRD1 623/4885 |
| US-20230065814-A1 | CONJUGATES OF-ELECTRON-PAIR-DONATING HETEROAROMATIC NITROGEN-COMPRISING COMPOUNDS | NQO1, NCL, ABCB1 | CCKBR 1515/4885CCKAR 1923/4885OPRD1 275/4885 |
| US-11559482-B2 | Biodegradable polyethylene glycol based water-insoluble hydrogels | PLG, PHYKPL, PLOD3 | CCKBR 631/4885CCKAR 1585/4885OPRD1 3338/4885 |
| US-11786599-B2 | Releasable conjugates | GUSB, ABCB11, UGT2B7 | CCKBR 1391/4885CCKAR 2453/4885OPRD1 623/4885 |
| US-20080255200-A1 | SUBSTITUTED BENZIMIDAZOLES | ABCB11, CYP2C19, HRH2 | CCKBR 104/4885CCKAR 539/4885OPRD1 620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.