Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | TPMT | P51580 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22490311 | 0.86 | TTR (0.35) | GAAKMT2AKDM4EMEN1KCNQ3 | |
| SCHEMBL2155225 | 0.84 | TTR (0.36) | KMT2AMEN1KCNQ3KCNQ2SMN1; SMN2 | |
| SCHEMBL11807871 | 0.82 | CA1 (0.48) | KMT2AKDM4EMEN1SMN1; SMN2HTT | |
| SCHEMBL2154502 | 0.82 | ALDH1A1 (0.38) | KMT2AMEN1KCNQ3KCNQ2SMN1; SMN2 | |
| SCHEMBL17946064 | 0.81 | MEN1 (0.47) | KMT2AMEN1HTTTPMTALDH1A1 | |
| SCHEMBL16338726 | 0.80 | CES2 (0.36) | HDAC1HDAC6KMT2AKCNQ3KCNQ2 | |
| SCHEMBL16384672 | 0.80 | TPMT (0.34) | KMT2AMEN1KCNQ3KCNQ2SMN1; SMN2 | |
| SCHEMBL11762810 | 0.78 | PKM (0.39) | GAAKDM4EALDH1A1 | |
| SCHEMBL12399061 | 0.78 | SMN1; SMN2 (0.46) | GAAMGAMAMY1ASIMGAM2 | |
| Ethane SCHEMBL29138437 | 0.77 | ALDH1A1 (0.37) | HDAC6HDAC8TPMTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2288652-B1 | PREPARATION FOR INITIATING RADICAL REACTIONS | UNITED INITIATORS GMBH & CO KG (DE) | 2012-09-19 | — | — | EP | claimed |
| US-20110272628-A1 | Preparation For Initiating Radical Reactions | UNITED INITIATORS GMBH (DE) | 2011-11-10 | — | — | US | claimed |
| EP-2288652-A1 | PREPARATION FOR INITIATING RADICAL REACTIONS | United Initiators GmbH & Co. KG (DE) | 2011-03-02 | — | — | EP | claimed |
| WO-2009146916-A1 | PREPARATION FOR INITIATING RADICAL REACTIONS | UNITED INITIATORS GMBH & CO. KG (DE) | 2009-12-10 | — | — | WO | claimed |
| EP-2130858-A1 | Preparations to initiate radical reactions | Degussa Initiators GmbH & Co. KG (DE) | 2009-12-09 | — | — | EP | claimed |
| CN-113999126-B | Preparation method of trimebutine | 浙江东亚药业股份有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-114014824-B | Application of heterocyclic compound | 上海科技大学 | 2023-06-13 | — | — | CN | disclosed |
| CN-114014824-A | Application of heterocyclic compound | 上海科技大学 | 2022-02-08 | — | — | CN | disclosed |
| CN-113999126-A | Preparation method of trimebutine | 浙江东亚药业股份有限公司 | 2022-02-01 | — | — | CN | disclosed |
| US-20180002709-A1 | RIBOSOME-MEDIATED INCORPORATION OF PEPTIDES AND PEPTIDOMIMETICS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-01-04 | — | — | US | disclosed |
| US-9682931-B2 | Aryloyl(oxy or amino)pentafluorosulfanylbenzene compound, pharmaceutically acceptable salt thereof, and prodrugs thereof | UBE INDUSTRIES, LTD. (JP) | 2017-06-20 | — | — | US | disclosed |
| US-20160244407-A1 | ARYLOYL(OXY OR AMINO)PENTAFLUOROSULFANYLBENZENE COMPOUND, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PRODRUGS THEREOF | UBE INDUSTRIES, LTD. (JP) | 2016-08-25 | — | — | US | disclosed |
| US-7875631-B2 | e.g.1-(3,5-dichlorophenyl)-2-formyl-6-methoxy-1,2,3,4-tetrahydroisoquinoline; to prevent and/or treat cancer and other abnormal cell growth, and metabolic as well as blood vessel proliferate disorders, in which uncontrolled expression of insulin-like growth factor-1 receptor is observed | ANALYTECON S.A. (CH) | 2011-01-25 | — | — | US | disclosed |
| WO-2009146916-A1 | PREPARATION FOR INITIATING RADICAL REACTIONS | UNITED INITIATORS GMBH & CO. KG (DE) | 2009-12-10 | — | — | WO | disclosed |
| EP-2130858-A1 | Preparations to initiate radical reactions | Degussa Initiators GmbH & Co. KG (DE) | 2009-12-09 | — | — | EP | disclosed |
| US-7528212-B2 | Ionizing radiation stable thermoplastic composition, method of making, and articles formed therefrom | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2009-05-05 | — | — | US | disclosed |
| US-20070117957-A1 | Ionizing radiation stable thermoplastic composition, method of making, and articles formed therefrom | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2007-05-24 | — | — | US | disclosed |
| US-4585866-A | Treatment of migraine with substituted tropyl benzoate derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-04-29 | — | — | US | disclosed |
| US-4563465-A | ANTISEROTONINE AGENTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-01-07 | — | — | US | disclosed |
| US-4001426-A | HAVING CORONARY VASODILATOR ACTIVITY | SMITHKLINE CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180002709-A1 | RIBOSOME-MEDIATED INCORPORATION OF PEPTIDES AND PEPTIDOMIMETICS | NPEPPS, DNPEP, AARS1 | GAA 2131/4885MGAM 873/4885AMY1A 4030/4885 |
| US-20160244407-A1 | ARYLOYL(OXY OR AMINO)PENTAFLUOROSULFANYLBENZENE COMPOUND, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PRODRUGS THEREOF | SLCO1B1, SLCO2B1, SLCO1B3 | GAA 1056/4885MGAM 1479/4885AMY1A 1027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.