Potassium Ion

Potassium Ion

SCHEMBL9856030

O=S(=O)([O-])C(F)(F)C(F)(F)C(F)(F)C(F)(F)S(=O)(=O)Cl.[K+]

nearest known ligand 0.33

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Known targets — ChEMBL curated mechanism

AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA

The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.33
CA1 P00915 2/20 0.33
MMP1 P03956 2/20 0.33
MMP2 P08253 2/20 0.33
MMP9 P14780 2/20 0.33
MMP8 P22894 2/20 0.33
MMP13 P45452 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Potassium Ion SCHEMBL9856218 0.95
SCHEMBL9855947 0.90
Potassium Ion SCHEMBL217908 0.87 CA2 (0.40) CA2CA1MMP1MMP2MMP9
Potassium Ion SCHEMBL9855746 0.84
Potassium Ion SCHEMBL2500523 0.84 CA2 (0.42) CA2CA1MMP1MMP2MMP9
SCHEMBL1455645 0.84 CA2 (0.38) CA2CA1MMP1MMP2MMP9
SCHEMBL2499938 0.81 CA2 (0.42) CA2CA1MMP1MMP2MMP9
Lithium Ion SCHEMBL3745424 0.81 CA2 (0.40) CA2CA1MMP1MMP2MMP9
Potassium Ion SCHEMBL2499167 0.81 CA2 (0.35) CA2CA1MMP1MMP2MMP9
Potassium Ion SCHEMBL126340 0.79 CA2 (0.52) CA2CA1MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0280392-B1 PREPARATION AND REACTIONS OF OMEGA-HALOSULFONYL PERFLUOROALKANESULFONATES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-08-28 EP disclosed
US-5011983-A Chemical intermediates, latent catalysts MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-04-30 US disclosed