Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | ICMT | O60725 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | S100A4 | P26447 | 2/20 | 0.35 |
| ▸ | CDC25A | P30304 | 2/20 | 0.35 |
| ▸ | CDC25B | P30305 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856019 | 0.83 | ALDH1A1 (0.35) | CA2CA12CA1CA7CA13 | |
| SCHEMBL9856324 | 0.81 | ALDH1A1 (0.47) | CA12CA1ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL9189810 | 0.80 | CA2 (0.41) | CA2CA12CA1ALDH1A1ICMT | |
| SCHEMBL4313725 | 0.79 | ALDH1A1 (0.48) | ALDH1A1MAPK1ICMTMTNR1AMTNR1B | |
| SCHEMBL9856252 | 0.78 | METAP2 (0.35) | ICMTMTNR1AMTNR1BGMNNLMNA | |
| SCHEMBL5846711 | 0.78 | SMN1; SMN2 (0.44) | ALDH1A1ICMTNPC1RAB9AMEN1 | |
| SCHEMBL8637757 | 0.78 | CA2 (0.61) | CA2CA12CA1CA7CA13 | |
| SCHEMBL9856329 | 0.75 | MTNR1A (0.50) | ALDH1A1MAPK1MTNR1AMTNR1BNPC1 | |
| SCHEMBL6091563 | 0.74 | METAP2 (0.33) | ICMTGMNNLMNACYP1A2CYP3A4 | |
| SCHEMBL9856327 | 0.74 | MTNR1A (0.53) | ALDH1A1MAPK1MTNR1AMTNR1BNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | disclosed |