Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 4/20 | 0.33 |
| ▸ | ICMT | O60725 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9189810 | 0.77 | CA2 (0.41) | METAP2ICMTGMNNTRPA1LMNA | |
| SCHEMBL6092776 | 0.77 | ADK (0.34) | METAP2PPARDPPARA | |
| SCHEMBL4313725 | 0.77 | ALDH1A1 (0.48) | METAP2ICMTGMNNTRPA1LMNA | |
| SCHEMBL5846711 | 0.76 | SMN1; SMN2 (0.44) | METAP2ICMTGMNNTRPA1LMNA | |
| SCHEMBL9856252 | 0.76 | METAP2 (0.35) | METAP2ICMTGMNNTRPA1LMNA | |
| SCHEMBL9856231 | 0.74 | CA2 (0.44) | METAP2ICMTGMNNTRPA1LMNA | |
| SCHEMBL9856019 | 0.73 | ALDH1A1 (0.35) | METAP2ICMTGMNNTRPA1LMNA | |
| SCHEMBL30586333 | 0.72 | SLC6A4 (0.42) | MAOAMAOBHDAC8 | |
| SCHEMBL9856324 | 0.71 | ALDH1A1 (0.47) | METAP2CYP3A4RECQLMAOBPPARD | |
| SCHEMBL21750687 | 0.69 | GAA (0.61) | LMNAPOLBCYP3A4MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006040644-A2 | PROCESSES FOR THE PREPARATION OF SUBSTITUTED THIOCHROMAN DERIVATIVES | RANBAXY LABORATORIES LIMITED (IN) | 2006-04-20 | — | — | WO | disclosed |