Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10394254 | 0.87 | MTNR1A (0.38) | MTNR1AMTNR1BALDH1A1NPC1USP2 | |
| SCHEMBL9856511 | 0.85 | L3MBTL1 (0.47) | MTNR1AMTNR1BALDH1A1NPC1USP2 | |
| SCHEMBL9856462 | 0.83 | USP2 (0.40) | MTNR1AMTNR1BALDH1A1NPC1USP2 | |
| SCHEMBL9856021 | 0.82 | MTNR1A (0.44) | MTNR1AMTNR1BALDH1A1NPC1USP2 | |
| SCHEMBL9856425 | 0.80 | ALDH1A1 (0.49) | MTNR1AMTNR1BALDH1A1NPC1USP2 | |
| SCHEMBL10394255 | 0.80 | USP2 (0.37) | MTNR1AMTNR1BALDH1A1USP2ALOX15 | |
| SCHEMBL10394858 | 0.79 | MTNR1A (0.48) | MTNR1AMTNR1BTSHRSMN1; SMN2LMNA | |
| SCHEMBL9856104 | 0.78 | LMNA (0.40) | ALDH1A1NPC1TSHRMAPK1ALOX5 | |
| SCHEMBL9856294 | 0.77 | PPARG (0.39) | ALDH1A1ALOX5PPARGPPARASMN1; SMN2 | |
| SCHEMBL9268024 | 0.77 | NR1I2 (0.49) | ALDH1A1USP2MAPK1ALOX5PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | claimed |
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | disclosed |