Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.60 |
| ▸ | CRHBP | P24387 | 1/20 | 0.60 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MGLL | Q99685 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | HRH2 | P25021 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7094774 | 0.84 | DRD2 (0.62) | MAPTCRHBPCRHR2L3MBTL1GAA | |
| SCHEMBL11886540 | 0.83 | NPC1 (0.65) | MAPTL3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL5402398 | 0.83 | CA12 (0.65) | MAPTGAALMNAMGLLALDH1A1 | |
| SCHEMBL9856035 | 0.81 | L3MBTL1 (0.59) | MAPTL3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL9190987 | 0.81 | KMT2A (0.63) | MAPTLMNAMGLLALDH1A1KMT2A | |
| SCHEMBL872557 | 0.81 | MGLL (0.47) | MAPTCRHBPCRHR2L3MBTL1GAA | |
| SCHEMBL9856606 | 0.80 | L3MBTL1 (0.54) | MAPTL3MBTL1LMNAALDH1A1KMT2A | |
| SCHEMBL16245558 | 0.80 | DRD2 (0.65) | MAPTCRHBPCRHR2L3MBTL1GAA | |
| SCHEMBL8603693 | 0.80 | MTNR1A (0.66) | MAPTL3MBTL1NPC1 | |
| SCHEMBL7558277 | 0.80 | ALDH1A1 (0.60) | MAPTCRHBPCRHR2L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | disclosed |