Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenyl Propionic Acid SCHEMBL9856748 | 0.85 | CTSG (0.43) | SLC6A2SLC6A4MEN1KMT2ACYP3A4 | |
| SCHEMBL9856897 | 0.79 | SLC6A2 (0.57) | SLC6A2SLC6A4MEN1KMT2ACYP3A4 | |
| SCHEMBL9856889 | 0.71 | TAAR1 (0.53) | SLC6A2SLC6A4MEN1KMT2ACYP3A4 | |
| SCHEMBL9857024 | 0.71 | SLC6A2 (0.50) | SLC6A2SLC6A4MEN1KMT2ACYP3A4 | |
| Lactic Acid SCHEMBL9856782 | 0.71 | TP53 (0.44) | SLC6A2SLC6A4CYP2D6CYP1A2TSHR | |
| SCHEMBL9857236 | 0.70 | HTR2A (0.53) | SLC6A2SLC6A4MEN1KMT2ACYP3A4 | |
| SCHEMBL9856174 | 0.70 | L3MBTL1 (0.51) | SLC6A2SLC6A4MEN1KMT2ACYP3A4 | |
| SCHEMBL9856754 | 0.69 | HPGD (0.39) | MEN1KMT2AAKR1C3HSP90AA1OPRK1 | |
| Sulfuric Acid SCHEMBL9856915 | 0.69 | HTR2A (0.45) | SLC6A2SLC6A4MEN1KMT2ACYP3A4 | |
| Sulfuric Acid SCHEMBL9856918 | 0.69 | HTR2A (0.45) | SLC6A2SLC6A4MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996235-A | Selectively inhibiting the uptake of serotonin and norepinephrine | ELI LILLY AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |
| EP-0318233-A2 | Improvements in or relating to serotonin and norepinephrine uptake inhibitors | ELI LILLY AND COMPANY (US) | 1989-05-31 | — | — | EP | disclosed |