Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenyl Propionic Acid SCHEMBL9856748 | 0.79 | CTSG (0.43) | HPGDCTSGCMA1HSP90AA1TAAR1 | |
| SCHEMBL9856745 | 0.69 | SLC6A2 (0.43) | HSP90AA1MEN1KMT2AAKR1C3OPRK1 | |
| SCHEMBL8900619 | 0.69 | HPGD (0.48) | HPGDTAAR1ALOX5MEN1KMT2A | |
| SCHEMBL9857052 | 0.69 | CTSB (0.42) | HPGDMEN1KMT2A | |
| SCHEMBL10595053 | 0.66 | CTSB (0.44) | HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL28439801 | 0.66 | AKR1C3 (0.54) | HPGDTAAR1ALOX5KMT2AAKR1C3 | |
| SCHEMBL9856989 | 0.65 | SLC6A2 (0.46) | MEN1KMT2A | |
| SCHEMBL28283295 | 0.65 | AKR1C3 (0.64) | HPGDTAAR1ALOX5MEN1KMT2A | |
| SCHEMBL9856790 | 0.64 | HPGD (0.39) | HPGDSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2397158 | 0.64 | LMNA (0.49) | HPGDCTSGCMA1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996235-A | Selectively inhibiting the uptake of serotonin and norepinephrine | ELI LILLY AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |