Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSG | P08311 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856745 | 0.85 | SLC6A2 (0.43) | HSP90AA1SLC6A2MEN1CYP1A2CYP3A4 | |
| SCHEMBL9856754 | 0.79 | HPGD (0.39) | CTSGCMA1HSP90AA1TAAR1MEN1 | |
| SCHEMBL9856897 | 0.77 | SLC6A2 (0.57) | SLC6A2MEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2397158 | 0.73 | LMNA (0.49) | CTSGCMA1FFAR1HPGDSMN1; SMN2 | |
| SCHEMBL8384207 | 0.70 | HTR2A (0.60) | TAAR1SLC6A2MEN1CYP1A2CYP3A4 | |
| SCHEMBL9856889 | 0.69 | TAAR1 (0.53) | TAAR1SLC6A2MEN1CYP1A2CYP3A4 | |
| SCHEMBL9857236 | 0.68 | HTR2A (0.53) | SLC6A2MEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9856174 | 0.68 | L3MBTL1 (0.51) | SLC6A2MEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8342049 | 0.68 | TAAR1 (0.53) | TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6301924 | 0.67 | LMNA (0.43) | CTSGCMA1MEN1KMT2AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996235-A | Selectively inhibiting the uptake of serotonin and norepinephrine | ELI LILLY AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |
| EP-0318233-A2 | Improvements in or relating to serotonin and norepinephrine uptake inhibitors | ELI LILLY AND COMPANY (US) | 1989-05-31 | — | — | EP | disclosed |