Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1616049 | 0.80 | LMNA (0.48) | LMNAPDGFRAKDRCYP1A2CYP2C9 | |
| SCHEMBL27303568 | 0.80 | KDR (0.49) | LMNAPDGFRAKDRCYP1A2CYP2C9 | |
| SCHEMBL7467432 | 0.78 | KDM4E (0.47) | PDGFRAKDRTRPA1CYP1A2CYP3A4 | |
| SCHEMBL9598026 | 0.75 | MEN1 (0.43) | LMNAPDGFRAKDRTRPA1CYP1A2 | |
| SCHEMBL7467603 | 0.75 | AR (0.49) | LMNAPDGFRAKDRTRPA1CYP1A2 | |
| SCHEMBL9343289 | 0.74 | KMT2A (0.40) | LMNAKDRTRPA1CYP1A2CYP3A4 | |
| SCHEMBL1415534 | 0.74 | L3MBTL1 (0.42) | LMNACA12CA1CA2CA9 | |
| SCHEMBL9343291 | 0.74 | TGFBR1 (0.44) | LMNATRPA1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7460943 | 0.73 | PDGFRA (0.56) | PDGFRAKDRMET | |
| SCHEMBL9858688 | 0.73 | HCAR3 (0.47) | HCAR2LMNAKDM4EHTTSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3086881-A | — | — | None | — | — | JP | disclosed |
| JP-H0386881-A | NAPHTHYLIDINE DERIVATIVE | ELI LILLY & CO | 1991-04-11 | — | — | JP | disclosed |
| EP-0410762-A1 | Naphthyridine derivatives | DowElanco (US) | 1991-01-30 | — | — | EP | disclosed |