Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | RHEB | Q15382 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466638 | 0.80 | NR4A2 (0.53) | KDM4ESLC6A2SLC6A4SLC6A3NPC1 | |
| SCHEMBL11543918 | 0.77 | SLC6A2 (0.47) | KDM4ESLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL7458487 | 0.75 | NR4A2 (0.41) | KDM4ENPC1RAB9AGAAALDH1A1 | |
| SCHEMBL2657071 | 0.74 | NPC1 (0.50) | SLC6A2SLC6A4SLC6A3HTR1ANPC1 | |
| SCHEMBL27449031 | 0.74 | PTGS1 (0.49) | SLC6A2SLC6A4SLC6A3HTR1ANPC1 | |
| SCHEMBL9858367 | 0.73 | HCAR2 (0.45) | HCAR2KDM4EHTTLMNASCN9A | |
| SCHEMBL7464868 | 0.73 | MAPT (0.54) | NPC1GAAALDH1A1HPGDLMNA | |
| SCHEMBL1436765 | 0.73 | HPGD (0.59) | SLC6A2SLC6A4SLC6A3HTR1AALDH1A1 | |
| SCHEMBL20554261 | 0.72 | GAA (0.52) | KDM4ENPC1RAB9AGAAALDH1A1 | |
| SCHEMBL2323949 | 0.72 | KDM4E (0.48) | KDM4ESLC6A2HTR1ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410762-A1 | Naphthyridine derivatives | DowElanco (US) | 1991-01-30 | — | — | EP | disclosed |