Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953658 | 1.00 | TDP1 (0.42) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL10526514 | 0.82 | CYP2A6 (0.39) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL8600425 | 0.80 | ALDH1A1 (0.42) | TDP1TP53ALDH1A1CYP3A4 | |
| SCHEMBL29839690 | 0.80 | ALDH1A1 (0.42) | TDP1TP53ALDH1A1CYP3A4 | |
| SCHEMBL29807846 | 0.80 | TDP1 (0.42) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL8974919 | 0.80 | TDP1 (0.42) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL8148963 | 0.76 | CYP3A4 (0.41) | TP53CYP2A6RAPGEF4SMN1; SMN2CYP3A4 | |
| SCHEMBL9272780 | 0.76 | ALDH1A1 (0.52) | CYP1A2CYP2A6ALDH1A1MEN1KMT2A | |
| SCHEMBL2741041 | 0.76 | ACHE (0.35) | CYP1A2CYP2A6ALDH1A1ACHE | |
| SCHEMBL324210 | 0.76 | ALDH1A1 (0.35) | CYP2A6ALDH1A1MEN1KMT2ARAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1680218-A2 | SINGLE COMPONENT CATIONIC PALLADIUM PROINITIATORS FOR THE LATENT POLYMERIZATION OF CYCLOOLEFINS | Promerus, LLC (US) | 2006-07-19 | — | — | EP | claimed |
| US-20050187398-A1 | Single component cationic palladium proinitiators for the latent polymerization of cycloolefins | PROMERUS, LLC | 2005-08-25 | — | — | US | claimed |
| WO-2005042147-A2 | SINGLE COMPONENT CATIONIC PALLADIUM PROINITIATORS FOR THE LATENT POLYMERIZATION OF CYCLOOLEFINS | PROMERUS, LLC (US) | 2005-05-12 | — | — | WO | claimed |
| US-20230303522-A1 | ARYLTETRAHYDROPYRIDAZINE DERIVATIVE OR SALT THEREOF, INSECTICIDAL AGENT CONTAINING THE COMPOUND, AND METHOD OF USE THEREOF | NIHON NOHYAKU CO., LTD. (JP) | 2023-09-28 | — | — | US | disclosed |
| WO-2022154114-A1 | TRANSITION METAL COMPLEX/SILICON COMPOSITES AND CATALYST | 国立大学法人東京大学 | 2022-07-21 | — | — | WO | disclosed |
| US-20180162852-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LIMITED | 2018-06-14 | — | — | US | disclosed |
| US-20180161331-A1 | NOVEL TETRAHYDROPYRIDOPYRIMIDINE COMPOUND OR SALT THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2018-06-14 | — | — | US | disclosed |
| US-9926307-B2 | Compounds | MISSION THERAPEUTICS LTD (GB) | 2018-03-27 | — | — | US | disclosed |
| US-9889136-B2 | Tetrahydropyridopyrimidine compound or salt thereof | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2018-02-13 | — | — | US | disclosed |
| US-20170247365-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2017-08-31 | — | — | US | disclosed |
| US-9662333-B2 | Tetrahydropyridopyrimidine compound or salt thereof | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2017-05-30 | — | — | US | disclosed |
| US-20040219452-A1 | Dissolution rate modifiers for photoresist compositions | PROMERUS LLC | 2004-11-04 | — | — | US | disclosed |
| WO-2004076495-A2 | VINYL ADDITION POLYCYCLIC OLEFIN POLYMERS PREPARED WITH NON-OLEFINIC CHAIN TRANSFER AGENTS AND USES THEREOF | PROMERUS LLC (US) | 2004-09-10 | — | — | WO | disclosed |
| WO-2004074933-A2 | DISSOLUTION RATE MODIFIERS FOR PHOTORESIST COMPOSITIONS | PROMERUS LLC (US) | 2004-09-02 | — | — | WO | disclosed |
| US-4369189-A | INSECTICIDES, MITICIDES NEMATOCIDES | UNION CARBIDE CORPORATION (US) | 1983-01-18 | — | — | US | disclosed |
| US-4252815-A | ADRENERGIC BLOCKING AGENTS | MEAD JOHNSON & COMPANY (US) | 1981-02-24 | — | — | US | disclosed |
| US-4220468-A | Herbicidal 4-trifluoromethyl-4-nitrodiphenyl ethers | ROHM AND HAAS COMPANY (US) | 1980-09-02 | — | — | US | disclosed |
| US-4186131-A | CARDIOVASCULAR AGENTS | MEAD JOHNSON & COMPANY (US) | 1980-01-29 | — | — | US | disclosed |
| US-4186264-A | Triazapentadienes as acaricides | PFIZER INC. (US) | 1980-01-29 | — | — | US | disclosed |
| US-4128652-A | Triazapentadienes as acaricides | PFIZER INC. (US) | 1978-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180161331-A1 | NOVEL TETRAHYDROPYRIDOPYRIMIDINE COMPOUND OR SALT THEREOF | NR5A1, CYP17A1, AR | TDP1 1290/4885TP53 94/4885CYP1A2 997/4885 |
| US-20230303522-A1 | ARYLTETRAHYDROPYRIDAZINE DERIVATIVE OR SALT THEREOF, INSECTICIDAL AGENT CONTAINING THE COMPOUND, AND METHOD OF USE THEREOF | CYP4Z1, DDT, AADAC | TDP1 2463/4885TP53 4774/4885CYP1A2 115/4885 |
| US-20180162852-A1 | NOVEL COMPOUNDS | UCHL1, UCHL3, UCHL5 | TDP1 504/4885TP53 126/4885CYP1A2 2383/4885 |
| US-20170247365-A1 | NOVEL COMPOUNDS | UCHL1, UCHL3, UCHL5 | TDP1 504/4885TP53 126/4885CYP1A2 2383/4885 |
| US-20050187398-A1 | Single component cationic palladium proinitiators for the latent polymerization of cycloolefins | LRRK2, LBR, SNCA | TDP1 3233/4885TP53 4833/4885CYP1A2 3712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.