Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 4/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5190967 | 0.77 | LMNA (0.36) | TRPA1LMNAADRA1ACHRM1SLC6A2 | |
| SCHEMBL1981588 | 0.76 | LMNA (0.48) | TRPA1LMNAADRA1ACHRM1SLC6A2 | |
| SCHEMBL3918723 | 0.76 | ADRB2 (0.36) | TRPA1LMNAADRA1ACHRM1SLC6A2 | |
| SCHEMBL9862038 | 0.74 | ALDH1A1 (0.37) | TRPA1LMNAADRA1ACHRM1SLC6A2 | |
| SCHEMBL483998 | 0.73 | KDM4E (0.38) | TRPA1LMNAADRA1ACHRM1SLC6A2 | |
| SCHEMBL21195120 | 0.72 | TRPA1 (0.39) | TRPA1LMNAADRA1ACHRM1SLC6A2 | |
| SCHEMBL9861539 | 0.71 | GABRA1 (0.48) | TRPA1LMNASLC6A2HTR2BATM | |
| SCHEMBL24217828 | 0.70 | ADRB2 (0.42) | TRPA1LMNAADRA1ACHRM1SLC6A2 | |
| SCHEMBL5394172 | 0.70 | LMNA (0.52) | TRPA1LMNAADRA1ACHRM1SLC6A2 | |
| SCHEMBL2989000 | 0.70 | ADRB2 (0.42) | TRPA1LMNAADRA1ACHRM1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0032062-B2 | HIGH-MOLECULAR-WEIGHT NOVOLAK SUBSTITUTED PHENOLIC RESINS AND THEIR PREPARATION | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-10-16 | — | — | EP | disclosed |
| EP-0032062-B1 | HIGH-MOLECULAR-WEIGHT NOVOLAK SUBSTITUTED PHENOLIC RESINS AND THEIR PREPARATION | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1985-04-03 | — | — | EP | disclosed |
| US-4345054-A | High-molecular-weight novolak types substituted phenolic resins and process for preparation thereof | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1982-08-17 | — | — | US | disclosed |
| EP-0032062-A2 | High-molecular-weight novolak substituted phenolic resins and their preparation | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1981-07-15 | — | — | EP | disclosed |