Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.32 |
| ▸ | MAP2K6 | P52564 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.32 |
| ▸ | NEK10 | Q6ZWH5 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7836462 | 0.81 | GPR3 (0.42) | GPR3MAOAMAOBPDE4APDE4B | |
| SCHEMBL1641532 | 0.76 | PABPC1 (0.34) | HTTCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL9864633 | 0.73 | ALDH1A1 (0.35) | KMT2AALDH1A1HTTKDM4EHPGD | |
| SCHEMBL3181329 | 0.71 | GPR3 (0.59) | GPR3MAOAMAOBKMT2ANOS1 | |
| SCHEMBL10964206 | 0.70 | GPR3 (0.56) | GPR3MAOAMAOBKMT2ANOS1 | |
| SCHEMBL6785837 | 0.69 | MAOA (0.53) | GPR3MAOAMAOBKMT2APDE4B | |
| SCHEMBL29750439 | 0.69 | KMT2A (0.48) | MAOAMAOBKMT2ALMNATDP1 | |
| SCHEMBL28855974 | 0.68 | GPR3 (0.54) | GPR3MAOAMAOBKMT2ANOS1 | |
| SCHEMBL6227884 | 0.68 | GPR3 (0.54) | GPR3MAOAMAOBKMT2ANOS1 | |
| SCHEMBL22124889 | 0.68 | GPR3 (0.54) | GPR3MAOAMAOBKMT2ANOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150031686-A1 | PHENYL-OXAZOLYL DERIVATIVES, PREPARATION METHOD THEREOF, AND RELATED APPLICATION OF THE PHENYL-OXAZOLYL DERIVATIVES AS AN IMPDH INHIBITOR | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2015-01-29 | — | — | US | disclosed |
| US-4988695-A | Gastrointestinal disorders, antisecretory agents | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-01-29 | — | — | US | disclosed |
| EP-0380257-A2 | Condensed cinnoline derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1990-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150031686-A1 | PHENYL-OXAZOLYL DERIVATIVES, PREPARATION METHOD THEREOF, AND RELATED APPLICATION OF THE PHENYL-OXAZOLYL DERIVATIVES AS AN IMPDH INHIBITOR | IMPDH1, IMPDH2, IMPA1 | GPR3 4502/4885MAOA 176/4885MAOB 166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.