SCHEMBL9864182

SCHEMBL9864182

c1c[nH]c(Cc2cccc3cccnc23)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMD14 O00487 1/20 0.44
COPS5 Q92905 1/20 0.44
ALDH1A1 P00352 4/20 0.43
MAPT P10636 3/20 0.43
TDP1 Q9NUW8 3/20 0.43
LMNA P02545 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
NPC1 O15118 2/20 0.43
MAPK1 P28482 2/20 0.43
GAA P10253 1/20 0.43
RAB9A P51151 1/20 0.43
KDM4E B2RXH2 2/20 0.42
HTT P42858 2/20 0.42
MMP2 P08253 2/20 0.42
TSHR P16473 2/20 0.42
GMNN O75496 1/20 0.42
TP53 P04637 1/20 0.42
HSP90AA1 P07900 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27699962 0.81 MAPT (0.43) ALDH1A1MAPTMEN1KMT2AMAPK1
SCHEMBL3747110 0.76 DAO (0.41) PSMD14COPS5ALDH1A1MAPTTDP1
SCHEMBL4555597 0.75 RAB9A (0.56) PSMD14COPS5ALDH1A1MAPTLMNA
SCHEMBL1154872 0.73 TSHR (0.55) PSMD14COPS5ALDH1A1MAPTTDP1
SCHEMBL30003476 0.73 TSHR (0.55) PSMD14COPS5ALDH1A1MAPTTDP1
SCHEMBL28180473 0.73 ADRA2A (0.58) ALDH1A1MAPTTDP1LMNASMN1; SMN2
SCHEMBL9407051 0.73 PAX8 (0.53) PSMD14COPS5ALDH1A1MAPTTDP1
SCHEMBL1360579 0.72 TSHR (0.53) PSMD14COPS5ALDH1A1MAPTTDP1
Hydrochloric Acid SCHEMBL27297244 0.72 TSHR (0.53) PSMD14COPS5ALDH1A1MAPTTDP1
Naphthalene SCHEMBL17508960 0.71 ADRA2A (0.57) ALDH1A1MAPTTDP1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5062879-A 8-AZOLYLMETHYLQUINOLINES AND HERBICIDAL USE THEREOF BASF AKTIENGESELLSCHAFT (DE) 1991-11-05 US claimed
JP-2311476-A None JP disclosed
US-20150280147-A1 AROMATIC AZA-BICYCLIC COMPOUNDS CONTAINING CU, AG, AU, ZN, AL FOR USE IN ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2015-10-01 US disclosed
US-5062879-A 8-AZOLYLMETHYLQUINOLINES AND HERBICIDAL USE THEREOF BASF AKTIENGESELLSCHAFT (DE) 1991-11-05 US disclosed
JP-H02311476-A 8-AZOLYLMETHYLQUINOLINE BASF AG 1990-12-27 JP disclosed
EP-0399394-A1 8-Azolylmethylquinolines BASF Aktiengesellschaft (DE) 1990-11-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150280147-A1 AROMATIC AZA-BICYCLIC COMPOUNDS CONTAINING CU, AG, AU, ZN, AL FOR USE IN ELECTROLUMINESCENT DEVICES AOC2, AOC1, AOC3 PSMD14 1343/4885COPS5 524/4885ALDH1A1 306/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.