Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.32 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9864182 | 0.81 | PSMD14 (0.44) | MAPTPOLBKDM4EMEN1ALDH1A1 | |
| SCHEMBL7073450 | 0.73 | PAX8 (0.45) | MAPTPOLBKDM4EMEN1USP2 | |
| SCHEMBL25846851 | 0.70 | LOXL2 (0.52) | MAPTPOLBKDM4EMEN1USP2 | |
| SCHEMBL30002633 | 0.70 | MAPT (0.48) | MAPTPOLBKDM4EMEN1USP2 | |
| SCHEMBL8596016 | 0.70 | MAPT (0.48) | MAPTPOLBKDM4EMEN1USP2 | |
| SCHEMBL3820241 | 0.70 | MAPT (0.48) | MAPTPOLBKDM4EMEN1USP2 | |
| SCHEMBL2340487 | 0.70 | MAPT (0.48) | MAPTPOLBKDM4EMEN1USP2 | |
| SCHEMBL7119359 | 0.70 | ALDH1A1 (0.48) | MAPTPOLBKDM4EMEN1USP2 | |
| SCHEMBL18617684 | 0.70 | MAPT (0.48) | MAPTPOLBKDM4EMEN1USP2 | |
| SCHEMBL5545797 | 0.69 | MAPT (0.48) | MAPTPOLBKDM4EMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101107000-A | 3,6-bicyclolides | ENANTA PHARM INC (US) | 2008-01-16 | — | — | CN | disclosed |