Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 2/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11585690 | 0.72 | IDO1 (0.48) | LMNANOS1TDP1SMN1; SMN2CES1 | |
| SCHEMBL11794976 | 0.71 | KDM4E (0.44) | LMNATDP1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL3078052 | 0.71 | IDO1 (0.41) | LMNANOS1TDP1ALDH1A1CYP2C19 | |
| Urea SCHEMBL2006220 | 0.71 | FFAR1 (0.62) | LMNANOS1KEAP1TDP1MAPK1 | |
| Carbamic Acid SCHEMBL2222080 | 0.71 | FFAR1 (0.62) | LMNANOS1KEAP1TDP1MAPK1 | |
| SCHEMBL6049236 | 0.71 | NOS1 (0.64) | LMNANOS1KEAP1MAPK1SMN1; SMN2 | |
| SCHEMBL4185660 | 0.71 | ALDH1A1 (0.55) | NOS1TDP1SMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL13734757 | 0.70 | NOS1 (0.48) | LMNANOS1KEAP1MAPK1SMN1; SMN2 | |
| Phenylethyl Carbamate SCHEMBL111316 | 0.69 | LMNA (0.79) | LMNAKEAP1TDP1MAPK1SMN1; SMN2 | |
| SCHEMBL8990052 | 0.69 | CES1 (0.62) | LMNANOS1KEAP1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0427624-A1 | Thermoplastic elastomer based on polynorbornene and polyvinyl chloride | ELF ATOCHEM S.A. (FR) | 1991-05-15 | — | — | EP | disclosed |
| EP-0384822-A1 | Thermoplastic elastomer made of ethylene/alpha-olefin copolymer and polynorbornene | ELF ATOCHEM S.A. (FR) | 1990-08-29 | — | — | EP | disclosed |