Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10463060 | 0.94 | TSHR (0.44) | TSHRTDP1HCAR3HTTCHEK1 | |
| SCHEMBL9865389 | 0.84 | SNCA (0.44) | TSHRTDP1CHEK1SNCANPC1 | |
| SCHEMBL9864739 | 0.77 | LMNA (0.57) | TSHRTDP1HCAR3LMNARAB9A | |
| SCHEMBL111211 | 0.76 | MAPT (0.49) | TSHRTDP1HCAR3LMNANPC1 | |
| SCHEMBL29392600 | 0.76 | MAPT (0.49) | TSHRTDP1HCAR3LMNANPC1 | |
| SCHEMBL10494876 | 0.76 | HCAR3 (0.51) | TSHRTDP1HCAR3HTTLMNA | |
| SCHEMBL9866271 | 0.75 | ALDH1A1 (0.43) | TSHRTDP1LMNASNCANPC1 | |
| Hydrochloric Acid SCHEMBL9760985 | 0.75 | MAPT (0.48) | TSHRTDP1HCAR3LMNANPC1 | |
| SCHEMBL2893340 | 0.75 | HCAR3 (0.45) | TDP1HCAR3HTTCHEK1SNCA | |
| SCHEMBL11414367 | 0.73 | TSHR (0.43) | TSHRTDP1HTTCHEK1SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015769-A | Hair dyes formed by reaction of an alcohol with a phenol in the presence of a strong base for etherification followed by amination | L'OREAL (FR) | 1991-05-14 | — | — | US | disclosed |
| US-5011938-A | Antimicrobials | ELI LILLY AND COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| US-4940718-A | BACTERICIDES | ELI LILLY AND COMPANY (US) | 1990-07-10 | — | — | US | disclosed |
| US-4740622-A | 3-amino-4-nitrophenols, the process for preparation thereof and their use in dyeing keratinous fibres, and new intermediate 4,5-dinitrophenols | L'OREAL (FR) | 1988-04-26 | — | — | US | disclosed |