Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873089 | 0.85 | KCNH2 (0.39) | PDE4DMEN1KMT2AHSD11B1PDE2A | |
| SCHEMBL9936299 | 0.84 | HSD11B1 (0.36) | RAB9AMAPTTP53HSD11B1GPBAR1 | |
| SCHEMBL1086652 | 0.79 | PTGS1 (0.47) | RAB9ALMNAMAPTALDH1A1HPGD | |
| SCHEMBL3940018 | 0.75 | NR1H4 (0.42) | RAB9ANPSR1MAPTMEN1KMT2A | |
| SCHEMBL11593511 | 0.73 | PTGS1 (0.51) | RAB9AMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL1326560 | 0.70 | ALDH1A1 (0.44) | NPSR1LMNAMAPTALDH1A1KMT2A | |
| SCHEMBL14363632 | 0.68 | RAB9A (0.51) | RAB9ADUSP3PTPN11NPSR1HTR2B | |
| SCHEMBL167920 | 0.66 | — | — | |
| SCHEMBL440944 | 0.66 | TP53 (0.61) | PTPN11LMNAHTR2BPDE4DMAPT | |
| SCHEMBL29364307 | 0.66 | TP53 (0.61) | PTPN11LMNAHTR2BPDE4DMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011938-A | Antimicrobials | ELI LILLY AND COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| US-4940718-A | BACTERICIDES | ELI LILLY AND COMPANY (US) | 1990-07-10 | — | — | US | disclosed |
| EP-0202046-A1 | 7-Substituted bicyclic pyrazolidinones | ELI LILLY AND COMPANY (US) | 1986-11-20 | — | — | EP | disclosed |