Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 3/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865031 | 0.84 | RAB9A (0.40) | HSD11B1GPBAR1TP53MAPTNPC1 | |
| SCHEMBL1086652 | 0.77 | PTGS1 (0.47) | HSD11B1ATMGPBAR1TP53MAPT | |
| SCHEMBL6004541 | 0.73 | PTGS2 (0.39) | ATMGPBAR1TP53NPC1RAB9A | |
| SCHEMBL22347999 | 0.71 | HSD11B1 (0.41) | HSD11B1ABL1P2RX7DPP4 | |
| SCHEMBL600882 | 0.69 | — | — | |
| SCHEMBL1679666 | 0.69 | LMNA (0.44) | ATMGPBAR1MAPTNPC1 | |
| SCHEMBL1326560 | 0.68 | ALDH1A1 (0.44) | GPBAR1MAPTPTGS1PTGS2 | |
| Bromomethane SCHEMBL27781811 | 0.66 | MCL1 (0.39) | HSD11B1P2RX7NPC1RAB9APTGS1 | |
| SCHEMBL11593511 | 0.65 | PTGS1 (0.51) | GPBAR1TP53MAPTNPC1RAB9A | |
| SCHEMBL5777789 | 0.64 | FTO (0.42) | P2RX7GPBAR1TP53MAPTFTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651921-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2013-10-23 | — | — | EP | disclosed |
| US-20130253011-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-09-26 | — | — | US | disclosed |
| WO-2012080376-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130253011-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, NIT2 | HSD11B1 2773/4885ATM 2805/4885ABL1 1720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.