Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.68 |
| ▸ | NR1H4 | Q96RI1 | 8/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | MITF | O75030 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865584 | 0.87 | NAMPT (0.60) | NAMPTNR1H4HDAC1HDAC2HDAC3 | |
| SCHEMBL9339143 | 0.83 | PLAU (0.54) | NR1H4HDAC1HDAC2HDAC3RAB9A | |
| SCHEMBL6400257 | 0.83 | MGLL (0.72) | NR1H4RAB9AKMT2ANPC1MITF | |
| SCHEMBL991841 | 0.83 | HDAC1 (0.64) | NAMPTNR1H4HDAC1HDAC2HDAC3 | |
| SCHEMBL9867342 | 0.81 | NAMPT (0.59) | NAMPTNR1H4HDAC1HDAC2HDAC3 | |
| SCHEMBL996878 | 0.81 | NAMPT (0.78) | NAMPTHDAC1HDAC2HDAC3MAPK1 | |
| SCHEMBL995725 | 0.81 | NAMPT (1.00) | NAMPTHDAC1HDAC2HDAC3 | |
| SCHEMBL9867345 | 0.80 | NAMPT (0.52) | NAMPTNR1H4MAPK1 | |
| SCHEMBL27952268 | 0.79 | LMNA (0.70) | NAMPTHDAC2RAB9AKMT2ANPC1 | |
| SCHEMBL9879968 | 0.77 | HTT (0.60) | NR1H4RAB9AKMT2ANPC1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039805-A | Novel benzoic and phenylacetic acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 1991-08-13 | — | — | US | disclosed |