Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868430 | 0.91 | TOP1 (0.35) | TOP1HRH3S1PR1S1PR3MCHR1 | |
| SCHEMBL9866395 | 0.86 | TOP1 (0.37) | TOP1TSHRHRH3S1PR1S1PR3 | |
| SCHEMBL9866052 | 0.84 | MCHR1 (0.34) | TOP1MAPTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9602580 | 0.83 | MCHR1 (0.39) | TOP1MAPTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9864910 | 0.78 | L3MBTL1 (0.38) | MAPTALDH1A1GAAHTTMEN1 | |
| SCHEMBL9603147 | 0.78 | MCHR1 (0.35) | TOP1MAPTALDH1A1MCHR1ACHE | |
| SCHEMBL9602772 | 0.78 | MCHR1 (0.35) | TOP1MAPTALDH1A1GAAMCHR1 | |
| SCHEMBL9866558 | 0.76 | HRH3 (0.45) | HRH3 | |
| Fumaric Acid SCHEMBL9867501 | 0.75 | ALDH1A1 (0.35) | MAPTALDH1A1GAAMCHR1MEN1 | |
| Fumaric Acid SCHEMBL9867491 | 0.75 | ALDH1A1 (0.35) | MAPTALDH1A1GAAMCHR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0351435-A1 | FUSED PYRIDAZINE COMPOUNDS AND THEIR MEDICINAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1990-01-24 | — | — | EP | disclosed |