Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | TOP1 | P11387 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868430 | 0.93 | TOP1 (0.35) | MCHR1ACHETOP1MEN1KMT2A | |
| SCHEMBL9603147 | 0.90 | MCHR1 (0.35) | MCHR1ACHETOP1MEN1KMT2A | |
| SCHEMBL9602772 | 0.90 | MCHR1 (0.35) | MCHR1ACHETOP1GAAKDM4E | |
| SCHEMBL9865917 | 0.88 | MAOA (0.34) | ACHEGAASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9602580 | 0.87 | MCHR1 (0.39) | MCHR1ACHETOP1GAASMN1; SMN2 | |
| Fumaric Acid SCHEMBL9867501 | 0.85 | ALDH1A1 (0.35) | MCHR1GAAMEN1KMT2AKDM4E | |
| Fumaric Acid SCHEMBL9867491 | 0.85 | ALDH1A1 (0.35) | MCHR1GAAMEN1KMT2AKDM4E | |
| Fumaric Acid SCHEMBL9602836 | 0.85 | ALDH1A1 (0.34) | MCHR1GAAMEN1KMT2AKDM4E | |
| Fumaric Acid SCHEMBL9602842 | 0.85 | ALDH1A1 (0.34) | MCHR1GAAMEN1KMT2AKDM4E | |
| SCHEMBL9865229 | 0.84 | TOP1 (0.35) | MCHR1ACHETOP1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0351435-A1 | FUSED PYRIDAZINE COMPOUNDS AND THEIR MEDICINAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1990-01-24 | — | — | EP | disclosed |