Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 5/20 | 0.33 |
| ▸ | CA2 | P00918 | 5/20 | 0.33 |
| ▸ | CA9 | Q16790 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | HTR1F | P30939 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865854 | 0.82 | HCAR1 (0.39) | HCAR1CA1CA2CA9CA12 | |
| SCHEMBL9866531 | 0.79 | POLB (0.36) | HCAR1NFE2L2 | |
| SCHEMBL9866318 | 0.79 | ALDH1A1 (0.36) | HCAR1NFE2L2 | |
| SCHEMBL10745662 | 0.79 | TXNRD1 (0.34) | HCAR1NFE2L2HTR1DHTR1BHTR1F | |
| SCHEMBL9867762 | 0.77 | ALDH1A1 (0.37) | HCAR1NFE2L2 | |
| SCHEMBL9734248 | 0.77 | CA1 (0.38) | HCAR1NFE2L2CA1CA2HTR1D | |
| SCHEMBL10746083 | 0.77 | LMNA (0.37) | HCAR1NFE2L2MAPK1 | |
| SCHEMBL9865651 | 0.76 | HCAR1 (0.33) | HCAR1NFE2L2HTR1DHTR1BHTR1F | |
| SCHEMBL9735650 | 0.76 | HSD11B1 (0.43) | HCAR1 | |
| SCHEMBL9867057 | 0.76 | ALDH1A1 (0.35) | HCAR1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |
| CN-1042144-A | Pesticidal compound | ICI PLC (GB) | 1990-05-16 | — | — | CN | disclosed |
| EP-0356029-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-28 | — | — | EP | disclosed |