Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL10445020 | 0.99 | ALDH1A1 (0.35) | CA12CA1CA2CA9HRH3 | |
| SCHEMBL9602979 | 0.87 | MCHR1 (0.43) | CA12CA1CA2CA9HRH3 | |
| SCHEMBL9866678 | 0.85 | HRH3 (0.44) | HRH3ALDH1A1KMT2AMAPTPOLB | |
| Iodide SCHEMBL10445057 | 0.84 | HRH3 (0.43) | HRH3ALDH1A1KMT2AMAPTPOLB | |
| SCHEMBL9602675 | 0.80 | TOP1 (0.38) | CA12CA1CA2CA9HRH3 | |
| Iodide SCHEMBL9866676 | 0.79 | HRH3 (0.34) | HRH3KMT2A | |
| SCHEMBL9602962 | 0.78 | HRH3 (0.36) | CA12CA1CA2CA9HRH3 | |
| SCHEMBL9865213 | 0.77 | HRH3 (0.37) | HRH3ALDH1A1KMT2APTGS2MAPT | |
| SCHEMBL10560058 | 0.77 | MMP12 (0.44) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL9865465 | 0.76 | MCHR1 (0.38) | CA12CA1CA2CA9HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |