Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.31 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868894 | 0.86 | ALDH1A1 (0.36) | ALDH1A1ATM | |
| SCHEMBL9869020 | 0.85 | ALDH1A1 (0.37) | SCN9ASCN5AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11401796 | 0.85 | ALDH1A1 (0.52) | ALDH1A1KDM4EADRB2HTR6 | |
| SCHEMBL7322441 | 0.82 | KIF11 (0.41) | MAT2ASCN9ASCN5AKIF11 | |
| SCHEMBL11393569 | 0.80 | PSEN1 (0.37) | ALDH1A1 | |
| Flosequinan SCHEMBL5442796 | 0.80 | ATM (0.47) | SCN9AALDH1A1KDM4EATM | |
| SCHEMBL10590122 | 0.80 | MAT2A (0.42) | MAT2ASCN9ASCN5AALDH1A1PPARG | |
| Flosequinan SCHEMBL5441172 | 0.80 | ATM (0.47) | SCN9AALDH1A1KDM4EATM | |
| Flosequinan SCHEMBL122877 | 0.80 | ATM (0.47) | SCN9AALDH1A1KDM4EATM | |
| Flosequinan SCHEMBL6535622 | 0.79 | ATM (0.46) | SCN9AALDH1A1KDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991002724-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-03-07 | — | — | WO | disclosed |