Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 3/20 | 0.30 |
| ▸ | RAB9A | P51151 | 3/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9867248 | 0.86 | MAT2A (0.39) | ALDH1A1ATM | |
| SCHEMBL11401796 | 0.84 | ALDH1A1 (0.52) | ALDH1A1HTT | |
| SCHEMBL9869020 | 0.80 | ALDH1A1 (0.37) | ALDH1A1KMT2AMEN1HPGDHTT | |
| SCHEMBL11393569 | 0.79 | PSEN1 (0.37) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| Flosequinan SCHEMBL5442796 | 0.79 | ATM (0.47) | ALDH1A1KMT2AMEN1ATM | |
| Flosequinan SCHEMBL5441172 | 0.79 | ATM (0.47) | ALDH1A1KMT2AMEN1ATM | |
| Flosequinan SCHEMBL122877 | 0.79 | ATM (0.47) | ALDH1A1KMT2AMEN1ATM | |
| Flosequinan SCHEMBL6535622 | 0.78 | ATM (0.46) | ALDH1A1KMT2AMEN1ATM | |
| SCHEMBL7317623 | 0.77 | TP53 (0.38) | ALDH1A1KMT2A | |
| SCHEMBL9868991 | 0.77 | ALDH1A1 (0.38) | ALDH1A1BRD4BRPF1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991002724-A1 | THERAPEUTIC AGENTS | THE BOOTS COMPANY PLC (GB) | 1991-03-07 | — | — | WO | disclosed |