Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865784 | 0.86 | ALDH1A1 (0.42) | KDM4EALDH1A1KCNA5MAPK1LMNA | |
| SCHEMBL9867699 | 0.80 | ALDH1A1 (0.40) | KDM4EALDH1A1MAPK1TSHR | |
| Phosphoric Acid SCHEMBL9867536 | 0.80 | PTGS1 (0.46) | KDM4EALDH1A1KCNA5LMNATSHR | |
| SCHEMBL9867999 | 0.74 | PTGS1 (0.49) | DRD2HTR2CKDM4EALDH1A1KCNA5 | |
| SCHEMBL9868136 | 0.72 | ALDH1A1 (0.49) | KDM4EALDH1A1MAPK1LMNATSHR | |
| SCHEMBL7480157 | 0.65 | DRD2 (0.74) | DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL8041653 | 0.64 | DRD2 (0.64) | DRD2HTR2C | |
| SCHEMBL8041657 | 0.64 | DRD2 (0.64) | DRD2HTR2C | |
| SCHEMBL9867136 | 0.63 | ALDH1A1 (0.42) | ALDH1A1MAPK1 | |
| SCHEMBL14472858 | 0.63 | RIPK1 (0.43) | DRD2HTR2AHTR2CHTR2BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028715-A | 3-(3''-Aminoalkyl)-2-Arylthiazolidine Compounds | SOUTHWEST RESEARCH INSTITUTE (US) | 1991-07-02 | — | — | US | disclosed |