Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22163647 | 0.82 | PTGS1 (0.33) | TSHRSLC40A1SCN1ASCN5ASCN8A | |
| SCHEMBL9378913 | 0.80 | KIF18A (0.47) | ALDH1A1ALOX5APFEN1SMN1; SMN2MEN1 | |
| SCHEMBL9866654 | 0.80 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2MEN1KMT2ASLC40A1 | |
| SCHEMBL8212123 | 0.78 | SLC40A1 (0.53) | L3MBTL1ALDH1A1GAASMN1; SMN2RAB9A | |
| SCHEMBL12319048 | 0.78 | LOX (0.41) | ALDH1A1MEN1RAB9AKMT2ALMNA | |
| SCHEMBL9868009 | 0.77 | KEAP1 (0.48) | ALDH1A1MEN1KMT2ACA12CA1 | |
| SCHEMBL9866452 | 0.76 | ALDH1A1 (0.43) | ALDH1A1ALOX5APFEN1GAAKMT2A | |
| SCHEMBL9867995 | 0.75 | KMT2A (0.45) | L3MBTL1ALDH1A1GAASMN1; SMN2KMT2A | |
| SCHEMBL9866173 | 0.75 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2KMT2ACA12CA2 | |
| SCHEMBL27345695 | 0.74 | L3MBTL1 (0.36) | L3MBTL1ALDH1A1TSHRGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |
| EP-0356029-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-28 | — | — | EP | disclosed |