Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PKLR | P30613 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.39 |
| ▸ | PARG | Q86W56 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27349980 | 0.78 | ALDH1A1 (0.39) | KMT2ATDP1KDM4ERECQLSMN1; SMN2 | |
| SCHEMBL22163647 | 0.77 | PTGS1 (0.33) | — | |
| SCHEMBL9868435 | 0.75 | L3MBTL1 (0.38) | KMT2ASMN1; SMN2ALDH1A1LMNAGAA | |
| SCHEMBL9867726 | 0.74 | ALDH1A1 (0.39) | KMT2AKDM4ERECQLSMN1; SMN2ALDH1A1 | |
| SCHEMBL9867278 | 0.72 | ALDH1A1 (0.37) | KMT2AKDM4ERECQLSMN1; SMN2ALDH1A1 | |
| SCHEMBL9378913 | 0.71 | KIF18A (0.47) | KMT2AKDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9868009 | 0.71 | KEAP1 (0.48) | KMT2AALDH1A1PKMMAPT | |
| SCHEMBL9866654 | 0.71 | ALDH1A1 (0.38) | KMT2AKDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9865486 | 0.70 | KMT2A (0.43) | KMT2ARECQLSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL9376409 | 0.69 | CA2 (0.38) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |
| EP-0356029-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-28 | — | — | EP | disclosed |