Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9868339 | 0.81 | PTPN7 (0.52) | PTPN7MAPTPOLBNPC1RAB9A | |
| SCHEMBL9868414 | 0.67 | RAB9A (0.54) | PTPN7MAPTPOLBNPC1RAB9A | |
| SCHEMBL6771856 | 0.66 | ALDH1A1 (0.46) | RAB9AALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL8409033 | 0.65 | ALDH1A1 (0.54) | PTPN7MAPTPOLBRAB9AALDH1A1 | |
| SCHEMBL23407738 | 0.62 | NAMPT (0.69) | MAPTPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL20389255 | 0.62 | NAMPT (0.69) | MAPTPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL9868325 | 0.62 | MAPT (0.51) | MAPTPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL9868323 | 0.61 | MAPT (0.57) | PTPN7MAPTPOLBNPC1RAB9A | |
| SCHEMBL4358300 | 0.61 | ALDH1A1 (0.52) | PTPN7MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL9791819 | 0.61 | ALDH1A1 (0.61) | POLBALDH1A1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997667-A | Pyridinyl compounds of N-carbamoyl-N-thiocarbamoyl- or N-amidino-glycine or beta-alanine useful as sweetening agents | UNIVERSITE CLAUDE BERNARD (FR) | 1991-03-05 | — | — | US | disclosed |