Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866531 | 0.86 | POLB (0.36) | NFE2L2HCAR1 | |
| SCHEMBL9865651 | 0.82 | HCAR1 (0.33) | NFE2L2HCAR1 | |
| SCHEMBL9867957 | 0.81 | MEN1 (0.33) | NFE2L2CYP1A2CYP2C19HCAR1MEN1 | |
| SCHEMBL9867762 | 0.80 | ALDH1A1 (0.37) | NFE2L2KDM4EHCAR1 | |
| SCHEMBL10373802 | 0.79 | ALDH1A1 (0.41) | KDM4ECYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL9867797 | 0.78 | MEN1 (0.33) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL9866719 | 0.77 | L3MBTL1 (0.38) | KDM4ECYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL9869217 | 0.76 | KDM4E (0.33) | KDM4ECYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9869258 | 0.76 | NFE2L2 (0.33) | NFE2L2 | |
| SCHEMBL9865854 | 0.76 | HCAR1 (0.39) | HCAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |
| EP-0356029-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-28 | — | — | EP | disclosed |