Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870231 | 0.77 | LMNA (0.57) | MAPTLMNATSHRHPGDMMP13 | |
| SCHEMBL9870534 | 0.73 | PSD (0.62) | MAPTLMNATSHRHPGDMMP13 | |
| SCHEMBL9870591 | 0.71 | BRS3 (0.60) | MAPTLMNATSHRHPGDMMP13 | |
| SCHEMBL1890037 | 0.70 | GPR84 (0.67) | MAPTLMNATSHRHPGDMMP13 | |
| SCHEMBL30776798 | 0.70 | LMNA (1.00) | MAPTLMNATSHRHPGDMMP13 | |
| SCHEMBL9872522 | 0.70 | ALDH1A1 (0.62) | LMNATSHRHPGDMMP13ALDH1A1 | |
| SCHEMBL4136184 | 0.67 | SLC6A2 (0.49) | TSHRALDH1A1 | |
| SCHEMBL29068546 | 0.67 | MAPT (0.58) | MAPTLMNATSHRHPGDMMP13 | |
| SCHEMBL29391003 | 0.67 | MAPT (0.58) | MAPTLMNATSHRHPGDMMP13 | |
| SCHEMBL18063501 | 0.66 | HPGD (0.73) | MAPTLMNATSHRHPGDMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037830-A | Antisecretory-antiulcer agents | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1991-08-06 | — | — | US | disclosed |
| EP-0391254-A2 | Novel thiouracil derivatives pharmaceutical compositions containing them and process for preparing same | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1990-10-10 | — | — | EP | disclosed |