Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 3/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27492286 | 0.83 | CYP19A1 (0.52) | CYP17A1CYP19A1SMN1; SMN2TBXAS1CFTR | |
| SCHEMBL6259017 | 0.81 | AKR1C3 (0.57) | CYP17A1CYP19A1SMN1; SMN2TBXAS1CFTR | |
| SCHEMBL22899009 | 0.81 | CYP19A1 (0.51) | CYP17A1CYP19A1SMN1; SMN2TBXAS1CFTR | |
| SCHEMBL575045 | 0.81 | AKR1C3 (0.57) | CYP17A1CYP19A1SMN1; SMN2TBXAS1CFTR | |
| Hydrochloric Acid SCHEMBL4076278 | 0.80 | AKR1C3 (0.56) | CYP17A1CYP19A1SMN1; SMN2TBXAS1CFTR | |
| SCHEMBL30159419 | 0.80 | CYP17A1 (0.50) | CYP17A1CYP19A1SMN1; SMN2TBXAS1CFTR | |
| SCHEMBL17233832 | 0.80 | CYP17A1 (0.50) | CYP17A1CYP19A1SMN1; SMN2TBXAS1CFTR | |
| SCHEMBL27446830 | 0.80 | AKR1C3 (0.56) | CYP17A1CYP19A1SMN1; SMN2TBXAS1CFTR | |
| SCHEMBL4418464 | 0.80 | CYP19A1 (0.54) | CYP17A1CYP19A1SMN1; SMN2TBXAS1CFTR | |
| SCHEMBL17233924 | 0.80 | CYP17A1 (0.50) | CYP17A1CYP19A1SMN1; SMN2TBXAS1CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428660-B | Process for producing acetic acid | 国际人造丝公司 | 2022-02-15 | — | — | CN | disclosed |
| CN-107207392-B | Process for producing acetic acid | 国际人造丝公司 | 2021-06-08 | — | — | CN | disclosed |
| CN-108349865-B | Process for producing acetic acid | 国际人造丝公司 | 2021-05-11 | — | — | CN | disclosed |
| CN-107207391-B | Process for producing acetic acid | 国际人造丝公司 | 2020-11-06 | — | — | CN | disclosed |
| EP-3277654-B1 | PROCESSES FOR PRODUCING ACETIC ACID | CELANESE INT CORP (US) | 2020-08-12 | — | — | EP | disclosed |
| EP-3374342-B1 | PROCESSES FOR PRODUCING ACETIC ACID | CELANESE INT CORP (US) | 2020-07-08 | — | — | EP | disclosed |
| EP-3250545-B1 | PROCESSES FOR PRODUCING ACETIC ACID | CELANESE INT CORP (US) | 2019-06-26 | — | — | EP | disclosed |
| EP-3374342-A1 | PROCESSES FOR PRODUCING ACETIC ACID | Celanese International Corporation (US) | 2018-09-19 | — | — | EP | disclosed |
| US-9957216-B2 | Processes for producing acetic acid | CELANESE INTERNATIONAL CORPORATION (US) | 2018-05-01 | — | — | US | disclosed |
| EP-3277654-A1 | PROCESSES FOR PRODUCING ACETIC ACID | Celanese International Corporation (US) | 2018-02-07 | — | — | EP | disclosed |
| US-8455685-B2 | Acetic anhydride production by way of carbonylation with enhanced reaction and flashing | CELANESE INTERNATIONAL CORPORATION (US) | 2013-06-04 | — | — | US | disclosed |
| US-20130102809-A1 | Methanol Carbonylation Process with Rhodium Catalyst, an Iodide Salt and a Metallic Co-Catalyst Selected from Transition Metals, Indium, Strontium, Barium, Zinc, Tin and Heteropoly Acids | CELANESE INTERNATIONAL CORPORATION (US) | 2013-04-25 | — | — | US | disclosed |
| US-20130102810-A1 | Methanol Carbonylation Process with Rhodium Catalyst and a Lanthanide Metal Co-Catalyst | CELANESE INTERNATIONAL CORPORATION (US) | 2013-04-25 | — | — | US | disclosed |
| US-20120183450-A1 | ACETIC ACID PRODUCTION BY WAY OF CARBONYLATION WITH ENHANCED REACTION AND FLASHING | SCATES MARK O (US) | 2012-07-19 | — | — | US | disclosed |
| EP-2451766-A2 | ACETIC ACID PRODUCTION BY WAY OF CARBONYLATION WITH ENHANCED REACTION AND FLASHING | Celanese International Corporation (US) | 2012-05-16 | — | — | EP | disclosed |
| US-8168822-B2 | Acetic acid production by way of carbonylation with enhanced reaction and flashing | CELANESE INTERNATIONAL CORPORATION (US) | 2012-05-01 | — | — | US | disclosed |
| WO-2011159268-A1 | CARBONYLATION PROCESS | CELANESE INTERNALTIONAL CORPORATION (US) | 2011-12-22 | — | — | WO | disclosed |
| US-20110021816-A1 | Acetic anhydride production by way of carbonylation with enhanced reaction and flashing | CELANESE INTERNATIONAL CORPORATION | 2011-01-27 | — | — | US | disclosed |
| US-20110009665-A1 | Acetic acid production by way of carbonylation with enhanced reaction and flashing | CELANESE INTERNATIONAL CORPORATION | 2011-01-13 | — | — | US | disclosed |
| WO-2011005304-A2 | ACETIC ACID PRODUCTION BY WAY OF CARBONYLATION WITH ENHANCED REACTION AND FLASHING | CELANESE INTERNATIONAL CORPORATION (US) | 2011-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009665-A1 | Acetic acid production by way of carbonylation with enhanced reaction and flashing | DNMT1, SP1, ME1 | CYP17A1 581/4885CYP19A1 575/4885SMN1; SMN2 4351/4885 |
| US-20130102809-A1 | Methanol Carbonylation Process with Rhodium Catalyst, an Iodide Salt and a Metallic Co-Catalyst Selected from Transition Metals, Indium, Strontium, Barium, Zinc, Tin and Heteropoly Acids | CCNY, CA9, CA3 | CYP17A1 1251/4885CYP19A1 2290/4885SMN1; SMN2 1677/4885 |
| US-20110021816-A1 | Acetic anhydride production by way of carbonylation with enhanced reaction and flashing | CA3, CA4, CA2 | CYP17A1 1249/4885CYP19A1 1057/4885SMN1; SMN2 3983/4885 |
| US-20130102810-A1 | Methanol Carbonylation Process with Rhodium Catalyst and a Lanthanide Metal Co-Catalyst | ME1, MLYCD, SP1 | CYP17A1 1400/4885CYP19A1 1724/4885SMN1; SMN2 2512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.