Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9871084 | 0.89 | APP (0.37) | ACHEALDH1A1TSHRKDM4EMAPT | |
| SCHEMBL9871188 | 0.88 | KDM4E (0.37) | ALDH1A1TSHRRXFP1KDM4EMAPT | |
| SCHEMBL9870788 | 0.83 | KDM4E (0.42) | ALDH1A1TSHRRXFP1KDM4EMAPT | |
| SCHEMBL10963823 | 0.77 | ALDH1A1 (0.40) | ALDH1A1TSHRKDM4EMAPTGAA | |
| SCHEMBL9871963 | 0.77 | HTT (0.40) | ALDH1A1TSHRKDM4EMAPTGAA | |
| SCHEMBL9872191 | 0.76 | MAPT (0.38) | ALDH1A1TSHRKDM4EMAPTGAA | |
| SCHEMBL9871542 | 0.75 | ALDH1A1 (0.39) | ALDH1A1TSHRRXFP1KDM4EMAPT | |
| SCHEMBL9870678 | 0.74 | KDM4E (0.39) | ALDH1A1TSHRRXFP1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL9872400 | 0.74 | ALDH1A1 (0.39) | ALDH1A1TSHRRXFP1KDM4EMAPT | |
| SCHEMBL8793570 | 0.73 | LMNA (0.45) | ALDH1A1TSHRKDM4EMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011835-A | Substituted triazolopyridazines, pharmaceutical compositions and use | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-04-30 | — | — | US | claimed |
| US-5011835-A | Substituted triazolopyridazines, pharmaceutical compositions and use | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-04-30 | — | — | US | disclosed |