Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 4/20 | 0.43 |
| ▸ | TDO2 | P48775 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9429270 | 0.79 | TP53 (0.60) | ALDH1A1MEN1KMT2A | |
| SCHEMBL9429935 | 0.77 | MAPT (0.57) | ALDH1A1MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL9428850 | 0.69 | MEN1 (0.54) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL22777908 | 0.68 | MAPT (0.73) | ALDH1A1MEN1KMT2ANPSR1SMN1; SMN2 | |
| SCHEMBL9205131 | 0.68 | ALDH1A1 (0.81) | ALDH1A1MEN1KMT2ANPSR1KDM4E | |
| Hydrochloric Acid SCHEMBL9428878 | 0.68 | MEN1 (0.53) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL9429593 | 0.68 | SOD1 (0.57) | ALDH1A1MEN1KMT2A | |
| SCHEMBL9870796 | 0.66 | LMNA (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9310533 | 0.66 | RECQL (0.62) | KMT2ASMN1; SMN2KDM4ERECQL | |
| Hydrochloric Acid SCHEMBL9428320 | 0.66 | MEN1 (0.51) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5332739-A | Pyrimidinedione derivatives and antiarrhythmic agents containing same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-07-26 | — | — | US | disclosed |