Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.49 |
| ▸ | DRD3 | P35462 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873593 | 0.90 | DRD2 (0.57) | DRD2DRD3LMNAPOLBGAA | |
| SCHEMBL9873649 | 0.86 | SIGMAR1 (0.46) | DRD2LMNAPOLBGAAMAPT | |
| SCHEMBL9875015 | 0.81 | DRD2 (0.57) | DRD2DRD3LMNAPOLBGAA | |
| SCHEMBL9874358 | 0.80 | DRD2 (0.58) | DRD2DRD3LMNAPOLBGAA | |
| SCHEMBL9874743 | 0.78 | LMNA (0.51) | DRD2DRD3LMNAPOLBGAA | |
| SCHEMBL9874903 | 0.76 | SIGMAR1 (0.43) | DRD2DRD3LMNAPOLBGAA | |
| SCHEMBL9871472 | 0.75 | HTR1A (0.53) | DRD2DRD3DRD4 | |
| SCHEMBL9874113 | 0.74 | TSHR (0.47) | DRD2DRD3LMNAPOLBGAA | |
| SCHEMBL4483845 | 0.73 | DRD2 (0.64) | DRD2DRD3DRD4 | |
| SCHEMBL9874332 | 0.73 | DRD2 (0.61) | DRD2DRD3DRD4PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988699-A | Treatment of psychological disorders such as schizophrenia, as antipsychotic agents and hypotensive agents | WARNER-LAMBERT COMPANY (US) | 1991-01-29 | — | — | US | disclosed |