Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872977 | 0.83 | KDM4E (0.59) | KDM4EHTTHSD17B10ALDH1A1KMT2A | |
| Water SCHEMBL9874788 | 0.83 | KDM4E (0.58) | KDM4EHTTHSD17B10ALDH1A1KMT2A | |
| Water SCHEMBL9874791 | 0.83 | KDM4E (0.58) | KDM4EHTTHSD17B10ALDH1A1KMT2A | |
| SCHEMBL9872326 | 0.80 | LMNA (0.47) | HTTHSD17B10POLBLMNAGAA | |
| Water SCHEMBL9874025 | 0.79 | LMNA (0.46) | HTTHSD17B10POLBLMNAGAA | |
| Water SCHEMBL9874020 | 0.79 | LMNA (0.46) | HTTHSD17B10POLBLMNAGAA | |
| SCHEMBL3163995 | 0.78 | KDM4E (0.50) | KDM4EHTTHSD17B10ALDH1A1KMT2A | |
| SCHEMBL9873640 | 0.78 | DRD2 (0.47) | HTTHSD17B10POLBLMNAGAA | |
| SCHEMBL9871472 | 0.76 | HTR1A (0.53) | — | |
| SCHEMBL9874113 | 0.76 | TSHR (0.47) | KDM4EHTTHSD17B10ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988699-A | Treatment of psychological disorders such as schizophrenia, as antipsychotic agents and hypotensive agents | WARNER-LAMBERT COMPANY (US) | 1991-01-29 | — | — | US | disclosed |