Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.57 |
| ▸ | MGLL | Q99685 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11083860 | 0.81 | FAAH (0.54) | FAAHMGLLKMT2AGAAALDH1A1 | |
| SCHEMBL1108678 | 0.81 | MGLL (0.82) | FAAHMGLLRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL9527348 | 0.81 | TDP1 (0.56) | FAAHMGLLNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9529297 | 0.81 | ALDH1A1 (0.71) | FAAHMGLLNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9528419 | 0.81 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2HTTMEN1 | |
| SCHEMBL9528913 | 0.80 | HRH3 (0.50) | FAAHMGLLNPC1RAB9AHTT | |
| SCHEMBL9528259 | 0.78 | ALDH1A1 (0.49) | FAAHMGLLNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29386549 | 0.78 | DPP4 (0.56) | NPC1RAB9ASMN1; SMN2HTTMEN1 | |
| SCHEMBL8599235 | 0.77 | NPC1 (0.69) | NPC1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL1492483 | 0.77 | NPC1 (0.69) | NPC1SMN1; SMN2MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019611-A | Tetrahydrotriazinethiones | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0278890-A2 | Non-staining and slightly-staining antiozonants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-08-17 | — | — | EP | disclosed |