Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.71 |
| ▸ | FAAH | O00519 | 3/20 | 0.71 |
| ▸ | MGLL | Q99685 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4399380 | 0.83 | ALDH1A1 (1.00) | ALDH1A1FAAHMGLLLMNASMN1; SMN2 | |
| SCHEMBL9527348 | 0.82 | TDP1 (0.56) | ALDH1A1FAAHMGLLSMN1; SMN2NPC1 | |
| SCHEMBL9871967 | 0.81 | FAAH (0.57) | ALDH1A1FAAHMGLLSMN1; SMN2NPC1 | |
| SCHEMBL9528958 | 0.79 | HPGD (0.70) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL9528259 | 0.78 | ALDH1A1 (0.49) | ALDH1A1FAAHMGLLLMNASMN1; SMN2 | |
| SCHEMBL7430480 | 0.76 | HPGD (0.67) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL6444679 | 0.76 | ALDH1A1 (0.83) | ALDH1A1FAAHMGLLLMNAMAPT | |
| SCHEMBL9528913 | 0.73 | HRH3 (0.50) | ALDH1A1FAAHMGLLNPC1RAB9A | |
| SCHEMBL6265219 | 0.73 | ALDH1A1 (0.68) | ALDH1A1MGLLLMNASMN1; SMN2NPC1 | |
| SCHEMBL12692513 | 0.70 | ALDH1A1 (1.00) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252474-B1 | HYDRAZINE DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1993-04-21 | — | — | EP | disclosed |
| EP-0525832-A1 | Substituted 1,2,3- thiadiazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1993-02-03 | — | — | EP | disclosed |
| US-4916237-A | Substituted 1,2,3-thiadiazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1990-04-10 | — | — | US | disclosed |
| US-4803280-A | Substituted 1,2,3-thia-diazole-4-thiolates | AMERICAN CYANAMID COMPANY (US) | 1989-02-07 | — | — | US | disclosed |
| EP-0252474-A2 | Hydrazine derivatives | AMERICAN CYANAMID COMPANY (US) | 1988-01-13 | — | — | EP | disclosed |