Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872326 | 0.91 | LMNA (0.47) | DRD2DRD3 | |
| Water SCHEMBL9874025 | 0.90 | LMNA (0.46) | DRD2DRD3 | |
| Water SCHEMBL9874020 | 0.90 | LMNA (0.46) | DRD2DRD3 | |
| SCHEMBL9872840 | 0.77 | LMNA (0.54) | DRD2DRD3 | |
| SCHEMBL9872588 | 0.77 | DRD2 (0.55) | DRD2DRD3HTR1AADRA1A | |
| SCHEMBL9873640 | 0.75 | DRD2 (0.47) | DRD2DRD3 | |
| SCHEMBL9872473 | 0.74 | LMNA (0.40) | DRD2DRD3 | |
| SCHEMBL9871472 | 0.74 | HTR1A (0.53) | DRD2DRD3HTR1A | |
| SCHEMBL9873677 | 0.74 | KDM4E (0.47) | — | |
| SCHEMBL31143329 | 0.73 | GRIN2D (0.51) | DRD2DRD3ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988699-A | Treatment of psychological disorders such as schizophrenia, as antipsychotic agents and hypotensive agents | WARNER-LAMBERT COMPANY (US) | 1991-01-29 | — | — | US | disclosed |