Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.36 |
| ▸ | SCN4A | P35499 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874743 | 0.85 | LMNA (0.51) | LMNAPOLBGAAMAPTTSHR | |
| SCHEMBL9874903 | 0.81 | SIGMAR1 (0.43) | LMNAPOLBGAAMAPTTSHR | |
| SCHEMBL9874662 | 0.80 | SCN3A (0.39) | LMNAPOLBGAAMAPTTSHR | |
| SCHEMBL9873649 | 0.79 | SIGMAR1 (0.46) | LMNAPOLBGAAMAPTTSHR | |
| SCHEMBL9875211 | 0.76 | LMNA (0.45) | LMNAPOLBGAAMAPTTSHR | |
| SCHEMBL7315449 | 0.71 | LMNA (0.48) | LMNAPOLBGAAMAPTTSHR | |
| SCHEMBL322162 | 0.71 | LMNA (0.48) | LMNAPOLBGAAMAPTTSHR | |
| SCHEMBL320824 | 0.71 | DRD3 (0.46) | LMNAPOLBGAAMAPTTSHR | |
| Hydrochloric Acid SCHEMBL7325859 | 0.70 | ADRA2A (0.47) | LMNAPOLBGAAMAPTTSHR | |
| SCHEMBL6032898 | 0.70 | APOBEC3A (0.49) | LMNAPOLBGAAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988699-A | Treatment of psychological disorders such as schizophrenia, as antipsychotic agents and hypotensive agents | WARNER-LAMBERT COMPANY (US) | 1991-01-29 | — | — | US | disclosed |