Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874903 | 0.90 | SIGMAR1 (0.43) | SIGMAR1DRD2LMNAPOLBGAA | |
| SCHEMBL9872533 | 0.86 | DRD2 (0.49) | DRD2LMNAPOLBGAAMAPT | |
| SCHEMBL9872575 | 0.79 | LMNA (0.42) | SIGMAR1DRD2LMNAPOLBGAA | |
| SCHEMBL9874662 | 0.76 | SCN3A (0.39) | DRD2LMNAPOLBGAAMAPT | |
| SCHEMBL9873593 | 0.76 | DRD2 (0.57) | DRD2LMNAPOLBGAAMAPT | |
| SCHEMBL9874358 | 0.73 | DRD2 (0.58) | DRD2LMNAPOLBGAAMAPT | |
| SCHEMBL9367259 | 0.73 | SIGMAR1 (0.49) | SIGMAR1DRD2GAAMAPT | |
| SCHEMBL9873718 | 0.70 | LMNA (0.43) | DRD2LMNAPOLBGAAMAPT | |
| SCHEMBL9871472 | 0.70 | HTR1A (0.53) | DRD2 | |
| SCHEMBL9875015 | 0.68 | DRD2 (0.57) | DRD2LMNAPOLBGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988699-A | Treatment of psychological disorders such as schizophrenia, as antipsychotic agents and hypotensive agents | WARNER-LAMBERT COMPANY (US) | 1991-01-29 | — | — | US | disclosed |