Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873649 | 0.90 | SIGMAR1 (0.46) | SIGMAR1DRD2LMNAPOLBGAA | |
| SCHEMBL9873593 | 0.86 | DRD2 (0.57) | DRD2DRD4DRD3LMNAPOLB | |
| SCHEMBL9872575 | 0.81 | LMNA (0.42) | SIGMAR1DRD2DRD4DRD3LMNA | |
| SCHEMBL9874662 | 0.78 | SCN3A (0.39) | DRD2DRD3LMNAPOLBGAA | |
| SCHEMBL9873718 | 0.78 | LMNA (0.43) | DRD2DRD3LMNAPOLBGAA | |
| SCHEMBL9875015 | 0.78 | DRD2 (0.57) | DRD2DRD4DRD3LMNAPOLB | |
| SCHEMBL9872533 | 0.76 | DRD2 (0.49) | DRD2DRD4DRD3LMNAPOLB | |
| SCHEMBL9374318 | 0.73 | DRD2 (0.76) | SIGMAR1DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL7783718 | 0.72 | DRD2 (0.74) | SIGMAR1DRD2DRD4DRD3 | |
| SCHEMBL9874353 | 0.72 | DRD2 (0.55) | DRD2DRD3LMNAPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988699-A | Treatment of psychological disorders such as schizophrenia, as antipsychotic agents and hypotensive agents | WARNER-LAMBERT COMPANY (US) | 1991-01-29 | — | — | US | disclosed |